Lopend onderzoek en publicaties Pijncentrum

Lopend onderzoek

  • Data release study. ECAP-Controlled Closed-Loop SCS: Prospective Long-term European Real-world Outcomes.
  • Aggregate Patient Data Collection on Intellis neurostimulator (97715) for SCS for treatment of CBLP.
  • Objective long-term data recording of daily activity in patients with failed back surgery syndrome treated with spinal cord stimulation - a prospective 12-month follow-up study.
  • Multicenter Randomized Clinical Trial to Assess the Effect of Active versus Passive Recharge Burst Spinal Cord Stimulation in Failed Back Surgery (Burst-RAP)


  • Real-World Preliminary Data of ECAP-Controlled Closed-Loop SCS closely Match With Results of More Controlled Studies. https://www.neuromodulationjournal.org/article/S1094-7159(23)00414-2/fulltext. Nijhuis, Imaïl Gultüna, MD, Jan-Willem Kallewaard, MD, PhD, Johan van de Minkelis, MD, Willem-Jan Hofsté, MD, Emre Almac, MD, Lars Elzinga, MD, Birte Dietz, PHD, Frank Huygen, MD, PhD. Neuromodulation, Vol. 26, Issue 4, Supplement, S148, Published in issue: June, 2023.
  • Real-World Treatment Outcomes with ECAP-Controlled Closed-Loop Spinal Cord Stimulation: The Dutch Triangle Pain Clinic Experience. https://www.neuromodulationjournal.org/article/S1094-7159(23)00291-X/fulltextLars Elzinga, MD, Johan Van De Minkelis, MD, Hans Aukes, MD. Neuromodulation. Vol. 26. Issue 4, Supplement, S80, Published in issue: June, 2023.
  • Failure of Spinal Cord Stimulation for Neuropathic Pain After Spinal Cord Injury: A Case Report. https://www.neuromodulationjournal.org/article/S1094-7159(23)00592-5/fulltextL. Elzinga, MD. Neuromodulation. Vol. 26, Issue 4, Supplement, S243, Published in issue: June, 2023.
  • ECAP-controlled closed-loop spinal cord stimulation under normal clinical use in a real-world setting in the Netherlands. (https://www.sciencedirect.com/science/article/abs/pii/S1094715922008844?via%3Dihub). Nijhuis H, Hofsté WJ, Huygen F, Gültuna I, van de Minkelis J, Kallewaard JW, Elzinga L, Dietz, Almac. Neuromodulation. 2022 Oct 25(7):S100-S101. doi: 10.1016/j.neurom.2022.08.109. ISSN 1094-7159
  • Objective Long-Term Data Recording of Daily Activity Levels In Patients With Failed Back Surgery Syndrome Treated With Spinal Cord Stimulation: Track 3: Neurostimulation For Back And Leg Pain. https://www.neuromodulationjournal.org/article/S1094-7159(22)00899-6/fulltext. Kliment Gatzinsky, Bart Billet, Lars Elzinga, Jan Willem Kallewaard, Johannes Schapendonk, Eric Van Den Bosch, and others. Neuromodulation, Vol. 25, Issue 7, Supplement, S114, Published in issue: October, 2022.
  • Objective long-term data of daily activity in patients with persistent spinal pain syndrome type 2 (failed back surgery syndrome) treated with spinal cord stimulation. (https://www.sciencedirect.com/science/article/abs/pii/S1094715922008996?via%3Dihub). Gatzinsky K, Billet B, Elzinga L, Kallewaard JW, Schapendonk J, van den Bosch E, Zuidema X, Blazevic , Strandby, Meier K. Neuromodulation. 2022 Oct. 25(7):S114. doi: 10.1016/j.neurom.2022.08.124. ISSN 1094-7159
  • Comparing the Efficacy of Dorsal Root Ganglion Stimulation With Conventional Medical Management in Patients With Chronic Postsurgical Inguinal Pain: Post Hoc Analyzed Results of the SMASHING Study. (https://pubmed.ncbi.nlm.nih.gov/36456417/). Mol F, Scheltinga M, Roumen R, Wille F, Gültuna I, Kallewaard JW, Elzinga L, van de Minkelis J, Nijhuis H, Stronks DL, Huygen FJPM. Neuromodulation. 2022 Nov 28;S1094-7159(22)01347-2. doi: 10.1016/j.neurom.2022.09.014. Online ahead of print. PMID: 36456417
  • 10 kHz Spinal Cord Stimulation for the Treatment of Failed Back Surgery Syndrome with Predominant Leg Pain: Results from a Prospective Study in Patients from the Dutch Healthcare System. (https://pubmed.ncbi.nlm.nih.gov/33274545/). Kallewaard JW, Gültuna I, Hoffmann V, Elzinga L, Munnikes R, Verbrugge L, Minne V, Reiters P, Subbaroyan J, Santos A, Rotte A, Caraway D. Pain Pract. 2021 Jun;21(5):490-500. doi: 10.1111/papr.12973. Epub 2020 Dec 22. PMID: 33274545
  • Disability Improvements Using 10 kHz SCS for FBSS with Predominant Leg Pain: Dutch Healthcare System. https://www.neuromodulationjournal.org/article/S1094-7159(21)00025-8/pdf. Jan Kallewaard, MD, Ismail Gültuna, MD, Vincent Hoffmann, MD, Lars Elzinga, MD, Renate Munnikes, MD, Lisette Verbrugge, MD, Anand Rotte, PhD, Veerle Minne, MSc, Angela Santos, David Caraway, MD, PhD. Neuromodulation. Vol. 24, Issue 4, e1–e276, Published in issue: June, 2021.
  • 10 kHz Spinal Cord Stimulation for Intractable Leg Pain: A Prospective Multicenter Dutch Study. https://www.neuromodulationjournal.org/article/S1094-7159(21)02133-4/pdf. Pascalle Reiters, MS, Jan Willem Kallewaard, PHD, Vincent Hoffmann, MD, PHD, Lars Elzinga, MD, Renate Munnikes, MD, Lisette Verbrugge, MD, Ismaïl Gültuna, MD, Veerle Minne, MSc, Pascalle Reiters, MS. Neuromodulation, Vol. 23, Issue 3, e1–e325, Published in issue: April, 2020.
  • Medical Management and 10 khz Spinal Cord Stimulation for the treatment of Non-Surgical Back Pain. https://www.neuromodulationjournal.org/article/S1094-7159(21)02220-0/pdf. Adnan A. Al-Kaisy, MD, Paul R. Eldridge, Prof, John Crossman, BSc MBBS MD FRCS (SN), Jan-Willem jw. Kallewaard, MD, FIPP, Lars L. Elzinga, MD, Ehab ES. Shiban, MD, Rudolf Likar, MSc, MD, Taissa Cherry, MD, Mark F. Sedrak, MD. Neuromodulation, Vol. 21, Issue 3, e1-e149, Published in issue: April, 2018.
  • High Frequency Spinal Cord Stimulation (HF-SCS) at 10kHz for the treatment of Intractable Leg Pain. https://www.neuromodulationjournal.org/article/S1094-7159(21)03358-4/pdf. Jan-Willem Kallewaard, MD, FIPP, Ismail Gultuna, MD, Vincent VL. Hoffmann, MD, PhD, Lars L. Elzinga,MD, Renate Munnikes,MD. Neuromodulation, Vol. 20, Issue 7, e122–e335, Published in issue: October, 2017.
  • COMPARING THE EFFICACY OF DORSAL ROOT GANGLIA STIMULATION WITH CONVENTIONAL MEDICAL MANAGEMENT FOR THE TREATMENT OF CHRONIC POST[1]SURGICAL INGUINAL PAIN: PRELIMINARY RESULTS OF THE SMASHING TRIAL. https://www.neuromodulationjournal.org/article/S1094-7159(21)03360-2/pdf. Frederique Mol, MD , Marc Scheltinga, PhD , Rudi Roumen, PhD , Frank Wille, PhD , Xander Zuidema, PhD , Harold Nijhuis, MD , Johan Van den Minkelis, MD , Lars Elzinga, MD , Jan-Willem Kallewaard, MD , Ismail Gultuna, MD , Jenni Breel, BSci , Frank Huygen, Prof. Neuromodulation, Vol. 20, Issue 7, e336–e783, Published in issue: October, 2017.