Lopend onderzoek en publicaties Interne Geneeskunde

Lopend onderzoek

• FLOW zorgevaluatie: flow dysfunction of hemodialysis vascular access: a randomized controlled trial on the effectiveness of surveillance of arteriovenous fistulas and graft
   
• Dialogica zorgevaluatie: DIALysis or not: Outcomes in older kidney patients with GerIatriC Assessment
   
• Renal life cycle trial
   
• Telemonitoring and E-coaching in Hypertension (TECH)- trial
   
• Obicetrapib on top of maximum tolerated lipid modifying therapies (BROOKLYN): a placebo controlled, double-blind randomized phase 3 study to evaluate the effect of obicetrapib in participants with a history of HeFH en aDL>70 mg/dL who are not adequately
   
• A randomised, single blind placebo-controlled, phase 2 study to investigate efficacy,  safety and tolerability of SLN360 in patients with elevated Lp(a) and stable cardiovascular disease.
   
• A double blind randomized placebocontrolled multicenter study assessing the impact of olparisan on major cardiovascular events in patients with atherosclerotic disease and elevated lipoproteine a.

 

Publicaties 

• Antihypertensive drug concentration measurement combined with personalized feedback in resistant hypertension: a randomized controlled trial. (https://pubmed.ncbi.nlm.nih.gov/37796233/). Peeters LEJ, Kappers MHW, Hesselink DA, van der Net JB, van de Laar R, Ezzahti M, van de Ven PJG, van der Meer IM, de Bruijne ELE, Indhirajanti-Tomasoa S, van der Linde NAH, Bahmany S, Boersma E, Massy EK, van Dijk L, van Gelder T, Koch BCP, Versmissen J. Journal of Hypertension 2024 Jan 1; 42 (1):169-178. doi: 10.1097/HJH.0000000000003585. Epub 2023 Oct 18.
   
• Prevention and management of kidney graft failure. Bunthof K. (https://repository.ubn.ru.nl/handle/2066/296446). doi: 10.54195 / 9789493296213
   
• Can We Predict Graft Intolerance Syndrome After Kidney Transplant Failure? External Validation of a Previously Developed Model. (https://pubmed.ncbi.nlm.nih.gov/37213489/). Bunthof K, Saboerali K, Wetering JV, Nurmohamed A, Bemelman F, Zuilen AV, Brand JVD, Baas M, Hilbrands L. Transpl Int. 2023 May 5;36:11147. doi: 10.3389/ti.2023.11147. PMID: 37213489; PMCID: PMC10195885.
   
• Health-related quality of life, psychological distress, and fatigue in metastatic castration-resistant prostate cancer patients treated with radium-223 therapy. (https://pubmed.ncbi.nlm.nih.gov/35804188/). van der Doelen MJ, Oving IM, Wyndaele DNJ, van Basten JP, Terheggen F, van de Luijtgaarden ACM, Oyen WJG, van Schelven WD, van den Berkmortel F, Mehra N, Janssen MJR, Prins JB, Gerritsen WR, Custers JAE, van Oort IM.Prostate Cancer Prostatic Dis. 2023 Mar;26(1):142-150. doi: 10.1038/s41391-022-00569-8. Epub 2022 Jul 8.PMID: 35804188
   
• Physical Activity Is Associated with Improved Overall Survival among Patients with Metastatic Colorectal Cancer. (https://pubmed.ncbi.nlm.nih.gov/35205748/). Smit KC, Derksen JWG, Beets GLO, Belt EJT, Berbée M, Coene PPLO, van Cruijsen H, Davidis MA, Dekker JWT, van Dodewaard-de Jong JM, Haringhuizen AW, Helgason HH, Hendriks MP, Hoekstra R, de Hingh IHJT, IJzermans JNM, Janssen JJB, Konsten JLM, Los M, Mekenkamp LJM, Nieboer P, Peeters KCMJ, Peters NAJB, Pruijt HJFM, Quarles van Ufford-Mannesse P, Rietbroek RC, Schiphorst AHW, Schouten van der Velden A, Schrauwen RWM, Sie MPS, Sommeijer DW, Sonneveld DJA, Stockmann HBAC, Tent M, Terheggen F, Tjin-A-Ton MLR, Valkenburg-van Iersel L, van der Velden AMT, Vles WJ, van Voorthuizen T, Wegdam JA, de Wilt JHW, Koopman M, May AM, On Behalf Of The Plcrc Study Group. Cancers (Basel). 2022 Feb 16;14(4):1001. doi: 10.3390/cancers14041001. PMID: 35205748; PMCID: PMC8870120
   
• Health-related quality of life, psychological distress, and fatigue in metastatic castration-resistant prostate cancer patients treated with radium-223 therapy. (https://pubmed.ncbi.nlm.nih.gov/35804188/). van der Doelen MJ, Oving IM, Wyndaele DNJ, van Basten JP, Terheggen F, van de Luijtgaarden ACM, Oyen WJG, van Schelven WD, van den Berkmortel F, Mehra N, Janssen MJR, Prins JB, Gerritsen WR, Custers JAE, van Oort IM. Prostate Cancer Prostatic Dis. 2022 Jul 8. doi: 10.1038/s41391-022-00569-8. Online ahead of print. PMID: 35804188
   
• Monoclonal gammopathy of renal significance presenting with cryoblobulinaemia type I associaeted sever thrombotic microangiopathy. (https://pubmed.ncbi.nlm.nih.gov/35756736/). Hesius E, Bunthof KLW, Steenbergen E, de Kort E, Klein I, Wetzels J. Clin Kidney J. 2022 Mar 12;15(7):1425-1428. doi: 10.1093/ckj/sfac078. eCollection 2022 Jul. PMID: 35756736; PMCID: PMC9217659
   
• A randomized crossover study comparing different tacrolimus formulations to reduce intrapatient variability in tacrolimus exposure in kidney transplant recipients. (https://pubmed.ncbi.nlm.nih.gov/34905302/). Bunthof KLW, Al-Hassany L, Nakshbandi G, Hesselink DA, van Schaik RHN, Ten Dam MAGJ, Baas MC, Hilbrands LB, van Gelder T. Clin Transl Sci. 2022 Apr;15(4):930-941. doi: 10.1111/cts.13206. PMID: 34905302; PMCID: PMC9010272
   
• Diet-Exercise-Induced Hypokalemic Metabolic Alkalosis. (https://pubmed.ncbi.nlm.nih.gov/32442511/). Hoorn EJ, Bovée DM, Geerse DA, Visser WJ. Am J Med. 2020 Nov;133(11):e667-e669. doi: 10.1016/j.amjmed.2020.04.019. Epub 2020 May 20.